Low Ovarian Reserve (AMH Levels)
Ovarian reserve refers to the number of eggs a woman has in her ovaries. One of the most commonly used tests to assess ovarian reserve is the Anti-Müllerian Hormone (AMH) test.
- 1) What Is Low AMH (Ovarian Reserve Decline)?
- 2) Causes of Low Ovarian Reserve
- 3) Symptoms of Low Ovarian Reserve
- 4) How Is Low Ovarian Reserve Diagnosed?
- 5) Treatment for Low AMH (Ovarian Reserve Decline)
- 7) Can You Get Pregnant with Low AMH?
- 8) Does Low AMH Cause Irregular Periods?
- 9) What Are Normal AMH Levels?
- 10) Does Low AMH Prevent Pregnancy?
This hormone provides crucial insights into a woman’s reproductive potential and is measured through a simple blood test. Low AMH levels indicate a decline in ovarian reserve, which directly affects a woman’s ability to conceive naturally.
A decrease in ovarian reserve can significantly lower the chances of natural pregnancy. This condition is commonly observed in women of advanced age or those with reproductive health issues. However, low AMH does not mean pregnancy is impossible—with the right treatment and support, positive outcomes can still be achieved.
What Is Low AMH (Ovarian Reserve Decline)?
Women are born with a finite number of eggs, and this reserve gradually declines over time. As a woman ages, both the quantity and quality of eggs decrease. This process accelerates after age 35 and eventually leads to menopause when the ovarian reserve is completely depleted, making natural pregnancy no longer possible.
Causes of Low Ovarian Reserve
Low ovarian reserve is influenced by various factors, including:
- Age: The most significant factor affecting ovarian reserve is age. After 35, the decline in egg count speeds up, and by menopause, the reserve is completely depleted.
- Genetics: A family history of early menopause or genetic disorders can impact ovarian reserve.
- Reproductive Health Conditions: Certain conditions, such as endometriosis (chocolate cysts), autoimmune diseases, and other gynecological disorders, can lead to decreased egg count.
- Medical Treatments: Cancer treatments like chemotherapy and radiotherapy can damage ovarian tissue, reducing the egg supply.
- Surgical Interventions: Previous surgeries involving the ovaries may negatively affect ovarian reserve.
- Lifestyle Factors: Smoking, excessive alcohol consumption, exposure to environmental toxins, and poor lifestyle habits can contribute to diminished ovarian reserve.
Obesity and Metabolic Disorders: Excess weight can negatively impact both egg quality and quantity.
Symptoms of Low Ovarian Reserve
Low ovarian reserve does not always show obvious symptoms, and many women only discover it after struggling to conceive. However, certain signs may indicate a potential issue:
- Irregular menstrual cycles (shortened or prolonged cycles)
- Changes in menstrual flow (lighter or heavier bleeding)
- Shorter time between periods (a sign of declining AMH levels)
Decreased libido due to hormonal imbalances
How Is Low Ovarian Reserve Diagnosed?
Diagnosing low ovarian reserve requires blood tests and imaging techniques to evaluate follicle count and ovarian function. The key tests include:
- AMH Test: Measures Anti-Müllerian Hormone levels to assess ovarian reserve.
- FSH Test: High levels of Follicle-Stimulating Hormone (FSH) may indicate diminished ovarian function.
Ultrasound Scan: Evaluates antral follicle count (AFC) to determine the number of active follicles in the ovaries.
Treatment for Low AMH (Ovarian Reserve Decline)
How Is Low Ovarian Reserve Treated?
Women diagnosed with low AMH levels who wish to conceive can benefit from IVF (In Vitro Fertilization) treatment. At our clinic, we have helped numerous women with diminished ovarian reserve achieve pregnancy through personalized treatment protocols. Our advanced laboratory techniques and success-enhancing methods significantly improve pregnancy outcomes in low AMH cases.
For women who are not yet ready to conceive, we recommend egg freezing (oocyte cryopreservation). This allows them to preserve their fertility for future pregnancy.
Can You Get Pregnant with Low AMH?
Low AMH is one of the leading causes of infertility, but pregnancy is still possible with appropriate treatment. Women struggling to conceive due to low ovarian reserve can achieve pregnancy through IVF and fertility-enhancing treatments.
A personalized treatment plan designed by a fertility specialist can improve the chances of conception. In some cases, egg donation may be considered for women with severely diminished egg quality.
Does Low AMH Cause Irregular Periods?
Low AMH is associated with a decline in ovarian reserve, which may affect menstrual cycles. The reduced production of estrogen and progesterone due to low egg count can lead to irregular periods. However, not all women with low AMH experience menstrual irregularities—some may still have a regular cycle despite low hormone levels.
What Are Normal AMH Levels?
AMH levels vary based on age, individual health, and laboratory methods. The general reference ranges are:
- High AMH (>4.0 ng/mL): May indicate Polycystic Ovary Syndrome (PCOS).
- Normal AMH (1.0 – 4.0 ng/mL): Suggests a healthy ovarian reserve.
- Low AMH (0.5 – 1.0 ng/mL): Indicates a declining ovarian reserve.
- Very Low AMH (<0.5 ng/mL): Signifies a significantly reduced egg supply.
Since AMH levels alone do not determine fertility, it is crucial to evaluate them alongside FSH levels, antral follicle count, and overall health.
Does Low AMH Prevent Pregnancy?
Low AMH does not mean pregnancy is impossible, but it can reduce fertility potential. With the help of assisted reproductive technologies (ART), women with low ovarian reserve can increase their chances of conceiving.
A fertility specialist will assess each case individually and recommend the most suitable treatment options. If you have low AMH levels and want to learn more about your treatment options, you can contact us via WhatsApp or fill out our consultation form.